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DHFR Understanding the Role of Dihydrofolate ReductaseDihydrofolate reductase (DHFR) is a vital enzyme that plays a crucial role in various biochemical processes within the human body. This article explores the structure, function, and significance of DHFR, its involvement in folic acid metabolism, the medical applications of DHFR inhibitors, genetic variations associated with DHFR-related diseases, and the current research and future prospects surrounding DHFR.1. Introduction to DHFRDHFR, also known as dihydrofolate reductase, is an enzyme that facilitates the conversion of dihydrofolate (DHF) to tetrahydrofolate (THF) by utilizing NADPH as a cofactor. This conversion is a pivotal step in the metabolism of folic acid, which is essential for various biological processes in the body.2. The ...Read More
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